Tracking Neurodevelopmental Trajectory
TexGen's research output includes a fascinating study on Tracking the neurodevelopmental trajectory of beta band oscillations with optically pumped magnetometer-based magnetoencephalography. This study, published in eLife, delves into how neural oscillations mediate activity coordination within brain networks and support cognition and behavior. Understanding the developmental processes of these oscillations is crucial for both neuroscientific exploration and clinical applications. The research team, led by Rier, L. and Brookes, M. J., utilized optically pumped magnetometer-based magnetoencephalography to track the trajectory of beta band oscillations, shedding light on childhood development in this aspect.
Diagnostic Significance in Parkinson's Disease
An intriguing piece of research available on TexGen is the Swallow Tail Sign: Revisited, published in Radiology. The study conducted by Brammerloh, M. et al., investigates the radiologic swallow tail sign as a diagnostic marker for Parkinson's disease. This sign's loss in MRI scans of the substantia nigra has shown promise in diagnosing this condition. The study explores the anatomical underpinnings of this sign, enhancing our understanding of its diagnostic significance. By revisiting this sign, the research aims to contribute valuable insights into the diagnosis and management of Parkinson's disease.
Quantitative Magnetic Susceptibility in Brain Imaging
TexGen features a noteworthy research article on Phenotypic and genetic associations of quantitative magnetic susceptibility in UK Biobank brain imaging. Published in Nature Neuroscience, this study by Wang, C. et al., focuses on QSM as an MRI technique for measuring tissue magnetic properties. Identifying markers for assessing brain health and therapeutic interventions is a key goal in epidemiological neuroscience. By exploring the phenotypic and genetic associations of QSM, the researchers provide crucial insights into brain imaging and its potential implications for brain health assessment and treatment monitoring.
Understanding Cannabis Use Effects on Brain Development
One of the thought-provoking articles available on TexGen is the Bayesian causal network modeling study on adolescent cannabis use's effects on prefrontal cortical thinning. Published in Translational Psychiatry, this research by Owens, M. M. et al., uses BCN modeling to elucidate the probable causal relationships between cannabis use and prefrontal cortical thinning. While existing evidence links cannabis use to brain development differences, this study aims to uncover potential causal associations, enhancing our comprehension of the impact of adolescent cannabis use on brain structure.
Exploring Nutritional Effects on Diabetic Gastropathy
TexGen presents a Pilot Double-Blind Randomised Controlled Trial studying the Effects of Jejunal Nutrition on Postprandial Distress in Diabetic Gastropathy (J4G Trial). The research, published in Nutrients, conducted by Carneiro, L. et al., investigates the acute effects of jejunal enteral nutrition on postprandial distress in diabetic patients. Nausea, vomiting, and abdominal pain often accompany diabetic gastropathy, and JN could offer improvements in nutrition and glycemic control. The study's findings aim to enhance our understanding of nutritional interventions in managing postprandial distress in diabetic individuals.