Quantifiable Correlation of ToF-SIMS and XPS Data
The article titled "Quantifiable correlation of ToF-SIMS and XPS data from polymer surfaces with controlled amino acid and peptide content," published in 2022, explores the challenges in determining the biological response of peptide-coated surfaces in biomaterial design. The authors reveal the difficulties arising from instrumental limitations, lack of suitable model surfaces, and more. By studying the relationship between surface composition and biological behavior, this research promises significant advancements in biomaterial applications.
Structural and Biochemical Evaluation of Bisubstrate Inhibitors
The study titled "Structural and biochemical evaluation of bisubstrate inhibitors of protein arginine N-methyltransferases PRMT1 and CARM1 (PRMT4)," conducted in 2020, delves into the development of bisubstrate inhibitors targeting protein arginine methyltransferases PRMT1 and CARM1. These inhibitors hold promise for treating conditions like cardiovascular diseases and cancer, making them crucial targets for research. The research elucidates how these inhibitors could influence disease pathophysiology, offering new avenues for therapeutic approaches.
Enhancing Hand Hygiene Compliance in Children and Visitors
In the article "Improving children’s and their visitors’ hand hygiene compliance" from 2019, the focus is on a critical aspect often overlooked in healthcare interventions - hand hygiene compliance in children and their visitors. The study addresses the lack of attention given to this group's compliance and proposes strategies to enhance hygiene practices. By targeting both children and visitors, this research aims to reduce the transmission of infectious diseases and improve overall hygiene standards in healthcare settings.
Exploring Structure-Kinetic Profiling of Haloperidol Analogues
The research titled "Structure-Kinetic Profiling of Haloperidol Analogues at the Human Dopamine D2 Receptor," carried out in 2019, ventures into understanding the pharmacological profile of haloperidol analogues as dopamine D2 receptor antagonists. By comparing these analogues with atypical antipsychotic drugs like clozapine, the study sheds light on the potential side effects and therapeutic benefits associated with these compounds. This research provides valuable insights into the drug-receptor interactions that influence drug efficacy and side effect profiles.